(re: Phantasmagoria 2 in dos mode )
Look in your game’s installed folder for the configuration file, typically “RESOURCE.CFG” and open it in Notepad. Look for a line that points to your CD-ROM drive, or an “audio=” line. Be sure that this points to your CD-ROM (ie if your CD-ROM drive is D:, then “audio = D:”.) If this does not help, then try to re-install the game and let it install to the default location.